Part:BBa_K5441004

Probasin_Promoter

The probasin promoter, from the prostate-specific probasin gene, is a great tool for studying prostate cells. It's really responsive to androgens like testosterone, making it perfect for seeing how hormones affect prostate health and disease. It's strong and only works in the prostate, which is useful for:

Understanding prostate biology: Precisely controlling gene expression helps us understand normal function and disease mechanisms. Prostate cancer research: It helps build better models to test new treatments and understand tumor growth. Targeted therapies: Its prostate-specificity minimizes side effects in gene therapy. Synthetic biology: Its androgen-responsiveness lets us build "smart" treatments that adapt to hormone changes.

In particular, the property of PB promoter being activated in both cancerous and non-cancerous prostate cells allows it to be used along with other plasmid delivery systems like polymers.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]