Coding

Part:BBa_K5437013

Designed by: Yu-Li He   Group: iGEM24_Formosa   (2024-09-28)


MVAPP decarboxylase converts mevalonate-5-diphosphate (MVAPP) into isopentenyl diphosphate (IPP)

Mevalonate-5-diphosphate decarboxylase (MDD) is an enzyme that plays a key role in the mevalonate pathway, which is crucial for the biosynthesis of isoprenoids. MDD catalyzes the decarboxylation of mevalonate-5-diphosphate (MVAPP) to form isopentenyl diphosphate (IPP), a building block for various essential biomolecules like cholesterol, steroids, and terpenes. This reaction also releases carbon dioxide (CO₂) and is a critical step in the production of precursors for cellular processes such as membrane synthesis and protein prenylation.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 355
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None