Regulatory

Part:BBa_K5368002:Design

Designed by: Yifei Wu   Group: iGEM24_SCUT-China-B   (2024-10-02)


Tyr


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

1. Promoter Strength Assess the strength of the promoter to ensure it drives sufficient expression of the target gene. This can involve comparing the sequence with known strong or weak promoters. 2. Transcription Factor Binding Sites Identify and include essential transcription factor binding sites that are necessary for the regulation of the tyrosinase gene. This ensures proper activation in response to signaling pathways involved in melanogenesis.


Source

The mouse tyrosinase promoter (Tyr promoter) is derived from the genomic sequence of the mouse tyrosinase gene, which is located on chromosome 7.

References