Coding

Part:BBa_K5310014

Designed by: Ilias Pilianidis   Group: iGEM24_thessaloniki   (2024-10-01)


OX40 (CD134) signalling

The intracellular signaling domain of OX40 is crucial for promoting T cell survival, proliferation, and long-term immune responses. It enhances cytokine production. These are favourable to the prolonged survival of our proposed engineered T cell and any potential CAR or CAAR-T cell.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 88


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Categories
Parameters
None