Protein_Domain

Part:BBa_K5310011:Design

Designed by: Ilias Pilianidis   Group: iGEM24_thessaloniki   (2024-09-30)


CD3z signalling domain


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The sequence was retrieved from the NCBI database, the domain's use was evaluated in the literature, and the sequence was codon optimized for expression in human primary cell lines.


Source

The CD247 (CD3z) sequence is taken from the human genome, chromosome 1q24.2

References