Coding

Part:BBa_K5310009

Designed by: Ilias Pilianidis   Group: iGEM24_thessaloniki   (2024-09-30)


CD28 signalling

CD28 is an intrinsic T-cell protein that provides a complementary signal, assisting activation and minimizing depletion. It has key signaling motifs, notably YMNM and PYAP that initiate the P13K/Akt/mTOR and PDK1/Akt pathways respectively, both of which are involved in the cell cycle and cytokine production.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 116
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None