Protein_Domain

Part:BBa_K5310008:Design

Designed by: Ilias Pilianidis   Group: iGEM24_thessaloniki   (2024-09-30)


CD8a Transmembrane


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The sequence was retrieved from databases, the domain's use was evaluated in the literature, and the sequence was codon optimized for expression in human primary cell lines.


Source

CD8a -TMD is a known, well-performing domain derived from CD8, a membrane-bound glycoprotein involved in T cell antigen recognition. It is on chromosome 2 of the human genome.

References