Coding

Part:BBa_K5310007

Designed by: Ilias Pilianidis   Group: iGEM24_thessaloniki   (2024-09-29)


CD8a Hinge (homo sapiens codon optimized)

CD8a provides flexibility and appropriate spacing for the Chimeric Autoantibody Receptor. CD8a is an integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, it functions primarily as a coreceptor for MHC class I molecule:peptide complex.

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal PstI site found at 92
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal PstI site found at 92
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal PstI site found at 92
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal PstI site found at 92
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None