Coding

Part:BBa_K5286001

Designed by: Mara Valverde Rascón   Group: iGEM24_TUM-Straubing   (2024-09-22)


Cytosolic-abundant heat soluble protein 94063 (CAHS94063)

This coding part is involved in enhancing the survival of Hypsibius dujardini during desiccation and is part of the Cytosolically Abundant Heat Soluble (CAHS) proteins. It assists in maintaining cellular integrity and function by preventing damage caused by desiccation. This part belongs to the family of Intrinsically Disordered Proteins (IDP), which allows it to both interact with various cellular components, and harbors a vitrification property, which allows them to preserve the activity of the enzymes it protects, by preventing their organization into crystalline structures, which can be damaging to their integrity. When heterologously expressed, it can confer the same properties to cells of different species, and it can also preserve molecular components when added externally.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 459
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None