Part:BBa_K5238009
a suicide switch. Under conditions of intestinal hypoxia
The entire section is a suicide switch. Under conditions of intestinal hypoxia, the production of suicide proteins is inhibited, while extracellular factors can cause the expression of endoplasmic reticulum, leading to suicide Under low oxygen conditions,Hypoxia-inducible promoter will express transcription.Generate downstream SrpR repressor protein, which can bind to the SrpR promoter, blocking the expression of endoplasmic reticulum in Lactobacillus plantarum, thereby achieving inhibition of suicide in a simulated intestinal hypoxic environment. In a high oxygen environment, that is, a non intestinal environment, the expression of endoplasmic reticulum is not inhibited, achieving suicide against Lactobacillus plantarum
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 876
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1564
Illegal AgeI site found at 615 - 1000COMPATIBLE WITH RFC[1000]
| None |