Part:BBa_K5191004
Spermidine Synthase
Spermidine synthase is a key enzyme involved in polyamine biosynthesis, specifically converting putrescine into spermidine. This enzyme catalyzes the reaction between putrescine and decarboxylated S-adenosylmethionine (dcSAM), resulting in the formation of spermidine and methylthioadenosine. Spermidine plays a crucial role in cell growth and proliferation by influencing cell cycle regulation, gene expression, and responses to oxidative stress and nutrient deprivation. Additionally, it is associated with autophagy processes, potentially affecting cellular aging and lifespan, and it exhibits neuroprotective effects on neural cells. These functions highlight the significant role of spermidine synthase in cellular physiology and medical research.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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