DNA
Part:BBa_K4610004
Designed by: Sophie Geierstanger Group: iGEM23_CCA-San-Diego (2023-10-07)
The part BBa_K4610004 is the segment of DNA Afu8g00490. BBa_K4610004 encodes for the protein (Fma-KR). Once synthesized, Fma-KR is used in the fumagillin biosynthesis pathway for the stereo selective reduction of 5-keto-fumagillol (which is synthesized because of Fma-C6H (BBa_K4610002) and Fma-MT (BBa_K4610003)). This is a stereoselective keto-reductase to obtain fumagillol which is then used in the second part of the fumagillin biosynthesis pathway (Guruceaga et. al 2020).
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