Coding

Part:BBa_K4365029

Designed by: Svetlana Iarovenko   Group: iGEM22_TU_Dresden   (2022-09-30)


VEGF

This part contains yeast codon-optimized human VEGF-A (vascular endothelial growth factor). VEGF-A is a 165-aminoacids long (45kDa) secreted dimeric protein. In mammals, VEGF-A acts as an angiogenic factor and stimulates the growth and migration of endothelial cells[1].

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 67
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

  1. ↑ Apte RS, Chen DS, Ferrara N. VEGF in Signaling and Disease: Beyond Discovery and Development. Cell. 2019 Mar 7;176(6):1248-1264. doi: 10.1016/j.cell.2019.01.021. PMID: 30849371; PMCID: PMC6410740.
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Parameters
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