Coding

Part:BBa_K4156086

Designed by: Zheng Huang   Group: iGEM22_LZU-CHINA   (2022-10-06)


CCL21

CCL21 is an anti-tumor protein.


Usage and Biology

It activates host immune response through recruitment of T cells and dendritic cells.[1] CCL21 is used as a therapeutic component to confer therapeutic capability to engineered strains against CRC tumor cells.


References

1 Loeffler M, Le'Negrate G, Krajewska M, Reed JC. Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth. Cancer Immunol Immunother. May 2009;58(5):769-75. doi:10.1007/s00262-008-0555-9

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None