Part:BBa_K4085017
rcsA
Colanic acid synthesis in E. coli K-12 is regulated by the rcs system, which includes three positive regulators (RcsA, RcsB, and RcsF) and two negative regulators (RcsC and Lon). RcsB and RcsC act as the effector and the sensor, respectively, of a two-component regulatory system by stimulating capsule synthesis from colanic acid synthesis cps genes (36). The environmental signals which activate RcsC have yet to be determined. RcsA is an auxiliary factor which may interact with RcsB to form a heterodimer required for increased transcription of cps genes. In our project, the gene is one of the pair of heterologous positive regulators, RcsA and RcsB. They can attempte to promote GDP-L-fucose formation and thus 2′-FL production.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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