Part:BBa_K4020010

Usage and Biology

The scavenger receptor cysteine-rich (SRCR) domain is a highly conserved domain of about 110 residues. Most of the SRCR domains contain 6 to 8 cysteine residues which participate in the formation of disulfide bonds within the domain. SRCR appeared to be necessary for binding bacterial ligands (Blum et al., 2021; Yap et al., 2015). It is synthetic DNA.

References

• Blum, M., Chang, H. Y., Chuguransky, S., Grego, T., Kandasaamy, S., Mitchell, A., Nuka, G., Paysan-Lafosse, T., Qureshi, M., Raj, S., Richardson, L., Salazar, G. A., Williams, L., Bork, P., Bridge, A., Gough, J., Haft, D. H., Letunic, I., Marchler-Bauer, A., … Finn, R. D. (2021). The InterPro protein families and domains database: 20 years on. Nucleic Acids Research, 49(D1), D344–D354. https://doi.org/10.1093/NAR/GKAA977
• Yap, N. V. L., Whelan, F. J., Bowdish, D. M. E., & Golding, G. B. (2015). The Evolution of the Scavenger Receptor Cysteine-Rich Domain of the Class A Scavenger Receptors. Frontiers in Immunology, 0(JUN), 342. https://doi.org/10.3389/FIMMU.2015.00342