Coding
CsgC

Part:BBa_K3955000:Design

Designed by: Camilla Lane   Group: iGEM21_Lund   (2021-09-30)


Curli assembly protein CsgC


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Codon optimized for Limosilactobacillus reuteri.


Source

Source organism: E. coli Sequence before codon optimization: Uniprot, p52107, https://www.uniprot.org/uniprot/P52107

References

1. Evans M, Chorell E, Taylor J, Åden J, Götheson A, Li F et al. The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation. Molecular Cell. 2015;57(3):445-455.

2. Taylor J, Hawthorne W, Lo J, Dear A, Jain N, Meisl G et al. Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones. Scientific Reports. 2016;6(1).