Coding

Part:BBa_K364318:Experience

Designed by: Lior Malka   Group: iGEM10_Debrecen-Hungary   (2010-10-02)

This experience page is provided so that any user may enter their experience using this part.
Please enter how you used this part and how it worked out.

Physiological functions of NHR-80

NHR-80 encodes a nuclear hormone receptor, expressed in the intestine, that regulates expression of the delta-9 desaturases FAT-5/-6/-7, and thus regulates fatty acid metabolism; NHR-80 is fully required for any expression of FAT-7, full expression of FAT-5/-6, viability in the absence of FAT-6, and transcriptional hyperactivation of fat-7 in the absence of FAT-6, and for a fully normal adult lifespan.

Potential applications of NHR-80 LBD

This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules.

Applications of BBa_K364318

User Reviews

UNIQ27f2dda3aa70b734-partinfo-00000000-QINU UNIQ27f2dda3aa70b734-partinfo-00000001-QINU