Coding

Part:BBa_K3078005:Design

Designed by: Ziang Guo   Group: iGEM19_Jilin_China   (2019-10-11)


LL-37


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Frame shift mutation should be avoided.

Source

This sequence was collected from the part BBa_K1162006.

Organism: Homo sapiens (human)

References

[1]Luo X L, Li J X, Huang H R, et al. LL37 Inhibits Aspergillus fumigatus Infection via Directly Binding to the Fungus and Preventing Excessive Inflammation[J]. Front Immunol, 2019, 10: 283. 5-14

[2]Den Hertog A L, Van Marle J, Van Veen H A, et al. Candidacidal effects of two antimicrobial peptides: histatin 5 causes small membrane defects, but LL-37 causes massive disruption of the cell membrane[J]. Biochem J, 2005, 388(Pt 2): 689-95.