Coding
Part:BBa_K3003025:Design
Designed by: Merve Nida Baştürk Group: iGEM19_Bilkent-UNAMBG (2019-10-16)
Wild Type Insulin with a Linker Peptide (Rajpal 27)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This part was designed specifically considering the compatibility of chains with the linker sequences.
Source
Synthesized by IDT.
References
1.Fu, Z., R. Gilbert, E., & Liu, D. (2012). Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes. Current Diabetes Reviews, 9(1), 25–53.
2.Rajpal, G., Liu, M., Zhang, Y., & Arvan, P. (2009). Single-chain insulins as receptor agonists. Molecular endocrinology (Baltimore, Md.), 23(5), 679–688. doi:10.1210/me.2008-0349