Regulatory
Part:BBa_K2586000:Design
Designed by: Janek Meißner Group: iGEM18_Goettingen (2018-09-11)
Palf4: Constitutively active promoter for Bacillus subtilis
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The design advantage of the promoter is its length of only 30 bp. This makes it easy to introduce into a genetic system. Another advantage lays in the constitutive expression of the promoter: This allows for many sorts of different experiments.
Source
This part was originally described by Gundlach et. al. (Gundlach et. al. 2017). It was artificially designed to carry out experiments with the soil bacterium and model organism Bacillus subtilis.
References
(Gundlach et. al. 2017): Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis