Coding

Part:BBa_K2486102

Designed by: Tiago Lubiana Alves   Group: iGEM17_USP-Brazil   (2017-10-27)


Anti-malarial single-chain antibody m1C3

[theoretical part] [not assembled, not synthesized, not sent, not characterized]

Single chain antibody (scFvs) derived from mouse monoclonal antibodies, able to block Plasmodium falciparum, a malaria agent, in vivo.

GenBank: https://www.ncbi.nlm.nih.gov/nuccore/HQ315886

/Isaacs, Alison T., et al. "Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi." PLoS pathogens 7.4 (2011): e1002017

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal PstI site found at 70
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal PstI site found at 70
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal PstI site found at 70
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal PstI site found at 70
    Illegal AgeI site found at 649
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None