Coding
Part:BBa_K242200:Design
Designed by: Jesús Abraham Avelar Rivas Group: iGEM09_LCG-UNAM-Mexico (2009-10-20)
Colicin E3 rRNAse domain
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This biobrick is just the toxic domain for colicin E3. There is no domain of reception nor translocation.
Note: this colicin has also been reported to interact with eucaryotic ribosomes, so its use may imply effects on human health.
Source
Escherichia coli plasmid (pColE3)
References
Effect of Colicin E3 upon the 30S Ribosomal Subunit of Escherichia coli B. W. Senior and I. B. Holland