Part:BBa_K2220001
Flagellin self-assembly domains
The flagella filament is a helical structure composed of subunits of flagellin. And among various flagellin, the FliC has its own unique features. The N- and C-terminal regions of the FliC are important for filament formation, which are the D0 and D1 domain in Figure 8. The D3 domain is a central region of the Flic which plays no role in filament formation. Additionally, when FliC proteins are in the polymeric state, the D3 domain can be exposed on to the surface. Therefore, we can replace the central region of flagellin by other proteins without disturbing self-assembly. If we fuse the enzyme and FliC, we can obtain a filamentous material with high surface density of catalytic sites.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 777
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 301
- 1000COMPATIBLE WITH RFC[1000]
| None |