Regulatory
Part:BBa_K2209000:Design
Designed by: Qinyu Ge Group: iGEM17_Nanjing_NFLS (2017-10-17)
Modified promoter of aniline dioxygenase
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Protein binding to DNA which act the regulating factors in most of the gene expression. DNA sequence in promoter have consensus sequence, nucleotide in the consensus sequence mutated will largely affect the binding of regulating protein. So it could be change the level and pattern of the expression of the gene through the mutation of the promoter.
Source
P.putida and the similar strain such as pseudomonas