Regulatory
hucO
Part:BBa_K2197303:Design
Designed by: Ip Wang Chak Group: iGEM17_Hong_Kong_UCCKE (2017-08-10)
Repressor operator site for mammalian urate-dependent transsilencer (mUTS).
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
In the reference research article form ResearchGate, hucO motif originated from Deinococcus radiodurans R1 is replicated 8 times so that the chance of binding is higher. However, this design is very difficult to be synthesized chemically. Therefore, we reduce it to one tandem hucO.
Source
Deinococcus radiodurans R1