Protein_Domain

Part:BBa_K1935019:Design

Designed by: Emilie Gounin   Group: iGEM16_Bordeaux   (2016-10-14)


DNMT3a/DNMT3l


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 1464


Design Notes

Added link between Dnmt3a and Dnmt3l

Source

DNMT3A http://www.uniprot.org/uniprot/Q9Y6K1

DNMT3L http://www.uniprot.org/uniprot/Q9UJW3

References

Bernstein DL, Le Lay JE, Ruano EG, et al. TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts. J Clin Invest 2015; 125: 1998-2006