Device
Part:BBa_K1720003:Experience
Designed by: Ying Guan, Yuanbin Cui Group: iGEM15_SCUT-China (2015-08-27)
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Applications of BBa_K1720003
This part is a scilencing device targeting human phosphodiesterase 5A gene. PDE5A is a cGMP-specific phosphodiesterase. We used this part to up regulate the concentration of cGMP. cGMP is a second messenger in NO-sGC-cGMP pathway that can remit the myocardial hypertrophy by relaxing the vessels.
User Reviews
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