Plasmid
Part:BBa_K1391006:Experience
Designed by: Alexa Garcia Group: iGEM14_MIT (2014-10-16)
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Applications of BBa_K1391006
Spleen Tyrosine Kinase (Syk) is a tyrosine kinase that has a high affinity for the phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) of the CD79A and CD79B proteins (components of the B-Cell Receptor Complex). Syk binds to the phosphorylated ITAM and the ITAM then phosphorylates Syk allowing Syk to initiate a downstream signalling cascade that ordinarily results in the proliferation of B-Cells during clonal selection.
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