Difference between revisions of "Part:BBa K2985160"

Revision as of 01:01, 20 October 2019

P43-liaH->Lipopeptide tolerance gene

Enhanced tolerant genes for lipopeptides, so that the liaH gene will not be expressed only when the surfactin reaches a certain concentration, but will begin to synthesize a specific tolerance protein during the growth process, thus protecting Bacterial cells. The liaH gene cluster is mainly involved in the coding of the protein Lia protein, which can protect the integrity of the cell membrane. At the same time, liaH exists in the large gene cluster of lia, and the two-component system liaRS can effectively resist the damage of cells such as surfactin. It can enhance the tolerance of bacteria to lipopeptide antibiotics.

Sequence and Features

Assembly Compatibility:

10
INCOMPATIBLE WITH RFC[10]
Illegal EcoRI site found at 149
12
INCOMPATIBLE WITH RFC[12]
Illegal EcoRI site found at 149
21
INCOMPATIBLE WITH RFC[21]
Illegal EcoRI site found at 149
23
INCOMPATIBLE WITH RFC[23]
Illegal EcoRI site found at 149
25
INCOMPATIBLE WITH RFC[25]
Illegal EcoRI site found at 149
Illegal NgoMIV site found at 173
1000
COMPATIBLE WITH RFC[1000]

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K2985160 short</partinfo>
-Enhanced tolerance genes to lipopeptides, so that liaH genes will not only be expressed when surfactin reaches a certain concentration, but will begin to synthesize specific tolerance proteins during growth, thus protecting bacterial cells.
+Enhanced tolerant genes for lipopeptides, so that the liaH gene will not be expressed only when the surfactin reaches a certain concentration, but will begin to synthesize a specific tolerance protein during the growth process, thus protecting Bacterial cells.
+The liaH gene cluster is mainly involved in the coding of the protein Lia protein, which can protect the integrity of the cell membrane. At the same time, liaH exists in the large gene cluster of lia, and the two-component system liaRS can effectively resist the damage of cells such as surfactin. It can enhance the tolerance of bacteria to lipopeptide antibiotics.
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