Part:BBa_K4781003
Tat B - A protein of the TAT pathway complex
The twin arginine translocase (Tat) is a protein transport pathway that exists in archaea, bacteria, and plant chloroplasts. In bacteria, it exports proteins across the plasma membrane and is important for many processes, including energy metabolism, formation of the cell envelope, biofilm formation, heavy metal resistance, nitrogen-fixing symbiosis, bacterial pathogenesis and others [1], [2]. What makes this protein transport system unusual compared to other transport systems (such as the general secretory, or Sec pathway) is its ability to transport fully folded proteins across membranes. This remarkable feat has no requirement for ATP as an energy source and relies solely on the proton motive force (PMF).
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 403
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 104
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
//chassis/prokaryote/ecoli
| biology | In Escherichia coli and other Gram-negative bacteria, TatA, TatB, and TatC are all essential for efficient translocation. The twin arginine translocase (Tat) is a protein transport pathway that exists in archaea, bacteria, and plant chloroplasts. In bacteria, it exports proteins across the plasma membrane and is important for many processes, including energy metabolism, formation of the cell envelope, biofilm formation, heavy metal resistance, nitrogen-fixing symbiosis, bacterial pathogenesis and others . What makes this protein transport system unusual compared to other transport systems (such as the general secretory, or Sec pathway) is its ability to transport fully folded proteins across membranes. This remarkable feat has no requirement for ATP as an energy source and relies solely on the proton motive force (PMF). |
| chassis | E.coli |
| uniprot | P69425 |