Coding

Part:BBa_K364309:Experience

Designed by: Lior Malka   Group: iGEM10_Debrecen-Hungary   (2010-09-29)
Revision as of 22:56, 24 October 2010 by Lityupix (Talk | contribs) (→‎Physiological effects of ER)

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Physiological effects of ER

In the absence of hormone, estrogen receptors are largely located in the cytosol. Hormone binding to the receptor triggers a number of events starting with migration of the receptor from the cytosol into the nucleus, dimerization of the receptor, and subsequent binding of the receptor dimer to specific sequences of DNA. Some of the effects in humans: Createing proliferative endometrium,breast cell stimulation, increased body fat and weight gain, salt and fluid retention, increased risk of blood clots.

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