Composite

Part:BBa_K5459001

Designed by: Yu Han   Group: iGEM24_Squirrel-Shenzhen   (2024-09-25)
Revision as of 09:50, 25 September 2024 by Registry (Talk | contribs)

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J23119-BBa_B0034- CueR - BBa_B1005

CueR family proteins are key metal regulatory proteins in Escherichia coli that specifically sense monovalent copper ions (Cu⁺) in the internal and external cellular environment. CueR belongs to the MerR family of transcriptional regulators and plays a crucial role in regulating copper ion homeostasis and resistance to copper toxicity. When copper ion concentrations rise, CueR binds to copper ions with high affinity. Once copper ions enter the cell, CueR rapidly binds to them, triggering a conformational change in the CueR protein. When used in conjunction with BBa_K5459002, it can detect copper ion concentrations.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 7
    Illegal NheI site found at 30
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None