File:Model of pel regulation under the FleQ.jpeg
Revision as of 02:01, 28 September 2022 by Jiangzhelin (Talk | contribs) (FleQ binds to two FleQ boxes on the pel promoter (A). FleQ interacts with FleN in the absence of ATP (B) as well as in the presence of ATP, but in this case, it induces a distortion of pel DNA (C). We propose that FleN forms a bridge between two FleQ b...)
Model_of_pel_regulation_under_the_FleQ.jpeg (433 × 355 pixels, file size: 57 KB, MIME type: image/jpeg)
FleQ binds to two FleQ boxes on the pel promoter (A). FleQ interacts with FleN in the absence of ATP (B) as well as in the presence of ATP, but in this case, it induces a distortion of pel DNA (C). We propose that FleN forms a bridge between two FleQ bound to their binding sites. The binding of FleQ to FleQ box 2 is essential for repression. The binding of c-di-GMP to FleQ induces a conformational change of FleQ, probably propagated through FleN, which induces the relief of pel distortion and leads to pel expression (D). The binding of FleQ to FleQ box 1 is essential for activation.
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current | 02:01, 28 September 2022 | 433 × 355 (57 KB) | Jiangzhelin (Talk | contribs) | FleQ binds to two FleQ boxes on the pel promoter (A). FleQ interacts with FleN in the absence of ATP (B) as well as in the presence of ATP, but in this case, it induces a distortion of pel DNA (C). We propose that FleN forms a bridge between two FleQ b... |
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