Coding
Part:BBa_K3815007
Designed by: Hiroto Koga Group: iGEM21_Kyoto (2021-10-16)
Defensin1-Mxe GryA intein-PT-linker-His tag
This part is made of Hist tag for the peptide production. After producing peptide with His tag, it is recovered by Ni chromatography. Finally, adding DTT to it, we cut the N terminal of Mxe GyrA intein. Then, we can get the targeted protein.In this part, the targeted protein is Defencine1 derived from a honey bee. This is antimicrobial peptide that can inhibit the growth of gram-positive bacteria. In our experiment, we used it to kill the bacteria in the vase water.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 249
Illegal SpeI site found at 573 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 249
Illegal SpeI site found at 573 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 249
- 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 249
Illegal SpeI site found at 573 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 249
Illegal SpeI site found at 573
Illegal NgoMIV site found at 682 - 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |