Coding

Part:BBa_K3962350

Designed by: Siheng Li   Group: iGEM21_Leiden   (2021-10-13)
Revision as of 09:37, 13 October 2021 by Registry (Talk | contribs)

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HOK - Toxin in Hok/Sok

Sok is the antitoxin of the Hok/Sok toxin/antitoxin system. The Hok/Sok is a type I toxin/antitoxin system originating from the R1 plasmid in E. coli. The Sok transcript can bind with the leader region of Hok mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived hok toxin from the parent cell. Due to the short half-life of the sok antitoxin, daughter cells inherit only small amounts and it quickly degrades.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None