Generator
Part:BBa_K3962348:Design
Designed by: Siheng Li Group: iGEM21_Leiden (2021-10-12)
J23113 promoter regulated constant expression of toxin RelE
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 7
Illegal NheI site found at 30 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
J23113 promoter has low transcriptional activity. Using it to regulate the toxin gene can not only prevent high lethality, but also maintain its function. For Hok, it has also been used as a part of a kill switch. We used a PCR-based cloning method to clone the construct.
Source
All parts come from the iGEM registry.