Coding
Part:BBa_K3279008:Design
Designed by: Liang Siwen Group: iGEM19_CAU_China (2019-10-15)
cenA gene fused with INP-N sequence
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 333
Illegal BamHI site found at 733 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 75
Illegal NgoMIV site found at 408
Illegal AgeI site found at 1051
Illegal AgeI site found at 1414 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
The primary concern was BioBrick compatibility so that illegal sites in RFC[10] did not appear in the sequence. And the sequeces was finally designed to link with pET30a(+) , so we added restriction enzyme cutting site NdeI at the 5' and SalI at the 3'.
Source
cenA gene (BBa_K118023) is from Cellulomonas fimi genomic DNA. INP-N sequence (BBa_K3279006) is originally from Pseudomonas syringae's genomic sequence and we did a codon optimization.