Regulatory

Part:BBa_K2624000:Design

Designed by: Yunge Lou, Yali Wu   Group: iGEM18_CPU_CHINA   (2018-08-22)
Revision as of 13:32, 22 August 2018 by Registry (Talk | contribs)

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hTERT promoter


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Somatic mutations in the promoter of the gene for human telomerase reverse transcriptase (hTERT) are the most common noncoding mutations in cancer. Our design of this hTERT promoter (-146C>T, -138C>T, -139C>T) is according to such documented mutations.



Source

GenBank nucleotide sequence database, with mutations.

References