User:VolkerMorath

Virus Construction Kit

info AT biobricks DOT org

Dear Registry-Team,

my name is Volker Morath and I am a undergraduate from the iGEM Team Freiburg 2010. I am working on the description of our parts for the registry and wanted to sort them into the catalog. During this work I realised that all our parts that are designed to produce and modify therapeutical viral vectors based on the Adeno-associated virus do not belong to an already existing function-category. I have already created a function-category for viral vector production and a subcategory for the AAV that will be improved in the next days. The only remaining problem is that I can't create the category in the description of the corresponding BioBricks. [1]. If you are fine with my intention to sort our parts into the catalogue, could you please include the following categories:

//Viral vectors
//Viral vectors/AAV
//Viral vectors/AAV/RepCap
//Viral vectors/AAV/Vectorplasmid

Thanks a lot for your help in advance.

I am looking forward to see you all at the Yamboree.

Volker Morath (FreiGEM 2010)

Viral Vectors are modified viruses that are used in molecular biology to transfer genetic material into desired target cells. This process is called transduction when eucaryotic cells are the target.

Double stranded DNA Viruses

The Adenovirus

[http://expasy.org/viralzone/all_by_species/183.html Adenovirus]
200px
Group:	ds DNA Virus
Family:	Adenoviridae
Genus:	Mastadenovirus
Host range	Human, mammals
Capacity:	35000bp

The Simian virus 40

[]
200px
Group:	ds DNA Virus
Family:
Genus:
Host range
Capacity:

Single stranded DNA Viruses

The Adeno-associated Virus

[http://expasy.org/viralzone/all_by_species/226.html Adeno-associated Virus]
200px
Group:	ss DNA Virus
Family:	Parvoviridae
Genus:	Dependovirus
Host range	Human, vertebrates
Capacity:	4700bp

In the iGEM competition 2010 the Team Freiburg bioware constructed a Virus Construction Kit that makes the Adeno-associated virus (AAV2) available for all users of the parts registry. The Adeno-associated virus is a well studied vector for eukaryotic gene transfer.

Single stranded RNA retro-transcribing Viruses

The Lentivirus

[http://expasy.org/viralzone/all_by_species/264.html Lentivirus]
200px
Group:	ds DNA Virus
Family:	Retroviridae
Genus:	Lentivirus
Host range	Vertebrate
Capacity:	9750bp

References: 1)http://expasy.org/viralzone/

Loading.....

Loading.....

Loading.....

• 
• 
•