User:VolkerMorath

Virus Construction Kit

info AT biobricks DOT org

Dear Registry-Team,

my name is Volker Morath and I am a undergraduate from the iGEM Team Freiburg 2010. I am working on the description of our parts for the registry and wanted to sort them into the catalog. During this work I realised that all our parts that are designed to produce and modify therapeutical viral vectors based on the Adeno-associated virus do not belong to an already existing function-category. I have already created a function-category for viral vector production and a subcategory for the AAV that will be improved in the next days. The only remaining problem is that I can't create the category in the description of the corresponding BioBricks. [1]. If you are fine with my intention to sort our parts into the catalogue, could you please include the following categories:

//Viral vectors
//Viral vectors/AAV
//Viral vectors/AAV/RepCap
//Viral vectors/AAV/Vectorplasmid

Thanks a lot for your help in advance.

I am looking forward to see you all at the Yamboree.

Volker Morath (FreiGEM 2010)

Double stranded DNA Viruses

The Adenovirus

[http://expasy.org/viralzone/all_by_species/183.html Adenovirus]
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Group:	ds DNA Virus
Family:	Adenoviridae
Genus:	Mastadenovirus
Host range	Human, mammals
Capacity:	35000bp

Single stranded DNA Viruses

The Adeno-associated Virus

[http://expasy.org/viralzone/all_by_species/226.html Adeno-associated Virus]
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Group:	ss DNA Virus
Family:	Parvoviridae
Genus:	Dependovirus
Host range	Human, vertebrates
Capacity:	4700bp

In the iGEM competition 2010 the Team Freiburg bioware constructed a Virus Construction Kit that makes the Adeno-associated virus (AAV2) available for all users of the parts registry. The Adeno-associated virus is a well studied vector for eukaryotic gene transfer.

Single stranded RNA retro-transcribing Viruses

The Lentivirus

[http://expasy.org/viralzone/all_by_species/264.html Lentivirus]
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Group:	ds DNA Virus
Family:	Retroviridae
Genus:	Lentivirus
Host range	Vertebrate
Capacity:	9750bp

References: 1)http://expasy.org/viralzone/

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