User:Scmohr/Antibiotic-res cat page3

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This page has background information (including links) for antibiotic resistance.

Useful Information about Antibiotic Resistance

Links

Aminoglycoside Resistance

This category includes kanamycin, streptomycin, gentamycin, neomycin, tobramycin, amikacin...

http://www.antibioresistance.be/aminoglycosides.html

http://openwetware.org/wiki/Kanamycin

Tetracycline Resistance

This category includes three different resistance mechanisms. Related antibiotics are tetracycline, chlortetracycline, doxycycline, minocycline, oxytetracycline, spectinomycin. Note that the TetR gene encodes a very popular repressor that is frequently used in synthetic biology simply as a single control element in cells that do not express tetracycline resistance. [Check this.]

http://www.antibioresistance.be/Tetracycline/Menu_Tet.html

http://openwetware.org/wiki/Tetracycline

http://cmr.asm.org/cgi/content/abstract/5/4/387


Miscellaneous Information about Antibiotic Resistance in the Registry

1. Items with Antibiotic-inactivating Enzymes

Plasmids

The 98 well-characterized, available plasmids in the Registry, have the following resistance characteristics:

  • Ampicillin(A) -- 54
  • Chloramphenicol(C) -- 9
  • Gentamycin -- 0
  • Kanamycin(K)-- 9
  • Tetracycline(T)-- 2
  • AK -- 18
  • AC -- 2
  • AT -- 2
  • AG -- 1
  • AGK -- 1
BBa_K125000

Cells

BBa_V1016
BBa_V1019

2. Items with Membrane-blocking Proteins

3. Items with Membrane-embedded Efflux Pumps

Plasmids

BBa_J69602

4. Items with Altered Target Molecules

5. Containing Components of Alternative Metabolic Pathways