Regulatory
Part:BBa_K819002:Design
Designed by: YU Zhou Group: iGEM12_Peking (2012-09-02)
Revision as of 22:44, 25 September 2012 by Zhangzidong (Talk | contribs)
Luminesensor repressible recA408 promoter
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The original recA with the binding site of CTGT(N)8ACAG is mutated to CCGT(N)8ACGG, which is the 408 form.
The LexA408 protein has corresponding mutations of PA40, NS41 and AS42.
Source
The sequence of RecA was from [http://regulondb.ccg.unam.mx/gene?organism=ECK12&term=ECK120000814&format=jsp&type=gene RegulonDB]
The mutant promoter was synthesized by PCR and site directed mutagenesis