Difference between revisions of "Part:BBa K364320:Experience"
(→Possible applications of GAL4-NHR-8) |
|||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
| − | |||
===Physiological effects of NHR-8=== | ===Physiological effects of NHR-8=== | ||
| Line 16: | Line 15: | ||
===Applications of BBa_K364320=== | ===Applications of BBa_K364320=== | ||
| + | [[Image:nhr8pcdna.gif|800px|thumb|center|Picture of gel electrophoresis: Gal4-NHR8 in pCDNA3.1 resulting an insert of 953 bp.]] | ||
| + | |||
| + | [[Image:Team Debrecen WB pCDNA-Gal4-NHR8.jpg|800px|thumb|center|]] | ||
===User Reviews=== | ===User Reviews=== | ||
<!-- DON'T DELETE --><partinfo>BBa_K364320 StartReviews</partinfo> | <!-- DON'T DELETE --><partinfo>BBa_K364320 StartReviews</partinfo> | ||
Revision as of 17:31, 26 October 2010
Physiological effects of NHR-8
NHR-8 is required for gut function and may respond to the food signal.
The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine.This resembles the regulation of protective metabolic enzymes by xenobiotic-sensing nuclear receptors.
NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3.
Possible applications of GAL4-NHR-8
By the addition of lipid ligands(unknown), the created system activates the expression of any kind of genes fused to UAS(upstream activation seqence)previously. Also can be used as a lipid sensor by activating reporter genes (e.g. Luciferase).
Applications of BBa_K364320
User Reviews
UNIQ0103a83da01e3c0c-partinfo-00000000-QINU UNIQ0103a83da01e3c0c-partinfo-00000001-QINU