Difference between revisions of "Part:BBa K364314:Experience"
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NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3. | NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3. | ||
| − | ===Possible applications of | + | ===Possible applications of NHR-8 LBD=== |
This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules. | This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules. | ||
Latest revision as of 18:17, 25 October 2010
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Physiological functions of NHR-8
NHR-8 is required for gut function and may respond to the food signal.
The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine.This resembles the regulation of protective metabolic enzymes by xenobiotic-sensing nuclear receptors.
NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3.
Possible applications of NHR-8 LBD
This LBD can be fused with different DBDs forming a composite hormone receptor for ligand regulated expression of specific genes and can also be a sensor for various lipid natured molecules.
Applications of BBa_K364314
User Reviews
UNIQ4f0ed46825d2f8df-partinfo-00000000-QINU UNIQ4f0ed46825d2f8df-partinfo-00000001-QINU