Difference between revisions of "Part:BBa K364310:Experience"
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This experience page is provided so that any user may enter their experience using this part.<BR>Please enter | This experience page is provided so that any user may enter their experience using this part.<BR>Please enter | ||
how you used this part and how it worked out. | how you used this part and how it worked out. | ||
| − | === | + | ===Physiological effects of EcR=== |
| + | Pulses of 20-hydroxyecdysone occur during insect development, whereupon this hormone binds to the ecdysone receptor, a ligand-activated transcription factor found in the nuclei of insect cells.[1] This in turn leads to the activation of many other genes, as evidenced by chromosomal puffing at over a hundred sites. Ultimately the activation cascade causes physiological changes that result in ecdysis (moulting). | ||
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| + | ===Potential applications of EcR LBD=== | ||
| + | EcR LBD can be fused with different DBDs in order to activate downstream gene expression depending on the binding site of the DBD. | ||
===User Reviews=== | ===User Reviews=== | ||
Revision as of 23:11, 24 October 2010
This experience page is provided so that any user may enter their experience using this part.
Please enter
how you used this part and how it worked out.
Physiological effects of EcR
Pulses of 20-hydroxyecdysone occur during insect development, whereupon this hormone binds to the ecdysone receptor, a ligand-activated transcription factor found in the nuclei of insect cells.[1] This in turn leads to the activation of many other genes, as evidenced by chromosomal puffing at over a hundred sites. Ultimately the activation cascade causes physiological changes that result in ecdysis (moulting).
Potential applications of EcR LBD
EcR LBD can be fused with different DBDs in order to activate downstream gene expression depending on the binding site of the DBD.
User Reviews
UNIQ6e53de8357e610fa-partinfo-00000000-QINU UNIQ6e53de8357e610fa-partinfo-00000001-QINU