Difference between revisions of "Part:BBa K314202:Experience"

Latest revision as of 23:21, 21 October 2010

Evidence that Tse2 and Tsi2 work as expected

This evidence can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"

Applications of BBa_K314202

Tse2 and Tsi2 locus can be combined with the Type 6 Secretion System to result in a bacterium that targets other Gram-negative bacteria for killing. By placing your own regulation upstream of the Tse2Tsi2 locus, you can induce toxin expression whenever you like in order to control bacteria-bacteria killing.

This idea was used as a probiotic application (turning on the toxin in response to the detection of potentially pathogenic Gram-negative bacteria). This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].

User Reviews

UNIQ940eebbf914a07fa-partinfo-00000000-QINU UNIQ940eebbf914a07fa-partinfo-00000001-QINU

@@ Line 5: / Line 5: @@
 ===Applications of BBa_K314202===
-The Tse2/Tsi2 locus could be used in conjunction with a functioning T6 secretion system to produce a gram negative bacterial killing system. Different promoters could be used for the locus to tune toxin production to different signals.
+Tse2 and Tsi2 locus can be combined with the Type 6 Secretion System to result in a bacterium that targets other Gram-negative bacteria for killing.  By placing your own regulation upstream of the Tse2Tsi2 locus, you can induce toxin expression whenever you like in order to control bacteria-bacteria killing.
+This idea was used as a probiotic application (turning on the toxin in response to the detection of potentially pathogenic Gram-negative bacteria).  This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].
 ===User Reviews===