Difference between revisions of "Part:BBa K314201:Experience"

Revision as of 23:10, 21 October 2010

Evidence that Tsi2 works as expected can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"

Applications of BBa_K314201

Tsi2 is necessary for the generation of Gram-negative bacteria that have been directed to target other Gram-negative bacteria for killing by Tse2 in response to a user-defined signal. Tsi2 is necessary because it protects host cells from death caused by the Tse2 toxic protein.

If the antitoxin Tsi2 is combined with a functioning Type 6 Secretion System and the toxin Tse2 it results in a killing system that can be targeted to Gram-negative bacteria. This could be used in a probiotic application. This was the goal behind the Gram-negative portion of the [http://2010.igem.org/Team:Washington 2010 UW iGEM project].

User Reviews

UNIQe6adf94b09771661-partinfo-00000000-QINU UNIQe6adf94b09771661-partinfo-00000001-QINU

@@ Line 1: / Line 1: @@
 __NOTOC__
-This experience page is provided so that any user may enter their experience using this part.<BR>Please enter
-how you used this part and how it worked out.
 '''Evidence that Tsi2 works as expected can be found on [http://2010.igem.org/Team:Washington/Gram_Negative/Test this page] from the 2010 UW iGEM Wiki, under the heading "Evidence that Tse2 and Tsi2 are Function As Expected"'''