Difference between revisions of "Part:BBa K364303"
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is a critical checkpoint in C. elegans for acquisition of reproductive competence and for entry into | is a critical checkpoint in C. elegans for acquisition of reproductive competence and for entry into | ||
adulthood rather than dauer diapause. | adulthood rather than dauer diapause. | ||
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Revision as of 19:14, 1 September 2010
DAF-12 LBD
Caenorhabditis elegans nuclear receptor.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
The nuclear hormone receptor DAF-12 from Caenorhabditis elegans is activated by dafachronic acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450. DAF-12 activation is a critical checkpoint in C. elegans for acquisition of reproductive competence and for entry into adulthood rather than dauer diapause.