Difference between revisions of "Part:BBa K5382106"
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| − | The z domain refers to a synthetic protein domain that has the ability to bind to the Fc region of immunoglobulin G (IgG). In our project design, the z domain is used to construct extracellular vesicles (EVs) that can display antibodies, so that these EVs can bind specific antibodies through the z domain on their surface, so as to achieve targeted delivery to specific cells or tissues | + | The z domain refers to a synthetic protein domain that has the ability to bind to the Fc region of immunoglobulin G (IgG)<sup>[][][1]</sup>. In our project design, the z domain is used to construct extracellular vesicles (EVs) that can display antibodies, so that these EVs can bind specific antibodies through the z domain on their surface, so as to achieve targeted delivery to specific cells or tissues.<Br> |
| − | + | ===References=== | |
| + | [1] Oscar P B Wiklander;Doste R Mamand;Dara K Mohammad;Wenyi Zheng;Rim Jawad Wiklander;Taras Sych;Antje M Zickler;Xiuming Liang;Heena Sharma;Andrea Lavado;Jeremy Bost;Samantha Roudi;Giulia Corso;Angus J Lennaárd;Manuchehr Abedi Valugerdi;Imre Mäger;Evren Alici;Erdinc Sezgin;Joel Z Nordin;Dhanu Gupta;André Görgens;Samir El Andaloussi.Antibody-displaying extracellular vesicles for targeted cancer therapy.[J].Nature biomedical engineering,2024,() | ||
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===Usage and Biology=== | ===Usage and Biology=== | ||
Revision as of 10:16, 1 October 2024
z domain-protein domain
The z domain refers to a synthetic protein domain that has the ability to bind to the Fc region of immunoglobulin G (IgG)[][][1]. In our project design, the z domain is used to construct extracellular vesicles (EVs) that can display antibodies, so that these EVs can bind specific antibodies through the z domain on their surface, so as to achieve targeted delivery to specific cells or tissues.
References
[1] Oscar P B Wiklander;Doste R Mamand;Dara K Mohammad;Wenyi Zheng;Rim Jawad Wiklander;Taras Sych;Antje M Zickler;Xiuming Liang;Heena Sharma;Andrea Lavado;Jeremy Bost;Samantha Roudi;Giulia Corso;Angus J Lennaárd;Manuchehr Abedi Valugerdi;Imre Mäger;Evren Alici;Erdinc Sezgin;Joel Z Nordin;Dhanu Gupta;André Görgens;Samir El Andaloussi.Antibody-displaying extracellular vesicles for targeted cancer therapy.[J].Nature biomedical engineering,2024,() Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]